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Primary hypertrophic osteoarthropathy: an update
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《医学前沿(英文)》 2013年 第7卷 第1期 页码 60-64 doi: 10.1007/s11684-013-0246-6
Digital clubbing, which has been recognized as a sign of systemic disease, is one of the most ancient diseases. However, the pathogenesis of clubbing and hypertrophic osteoarthropathy has hitherto been poorly understood. The study of a clinically indistinguishable idiopathic form (primary hypertrophic osteoarthropathy, PHO) provides an opportunity to understand the pathogenesis of hypertrophic osteoarthropathy. Current advances in the study of PHO are discussed. The impaired metabolism of prostaglandin E2 (PGE2) plays a central role in its pathogenesis.
关键词: digital clubbing primary hypertrophic osteoarthropathy prostaglandin E2 (PGE2)
Sukhjot MANN, Zhiming QI, Shiv O. PRASHER, Lanhai LI, Dongwei GUI, Qianjing JIANG
《农业科学与工程前沿(英文)》 2017年 第4卷 第2期 页码 208-219 doi: 10.15302/J-FASE-2017138
关键词: adsorption degradation dissolved organic carbon 17β-estradiol (E2) estrone (E1)
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《医学前沿(英文)》 2016年 第10卷 第1期 页码 76-84 doi: 10.1007/s11684-015-0426-7
Anti-β2 glycoprotein I (anti-β2GP I ) antibodies are important contributors to thrombosis, especially in patients with antiphospholipid syndrome (APS). However, the mechanism by which anti-β2GP I antibodies are involved in the pathogenesis of thrombosis is not fully understood. In this report, we investigated the role of anti-β2GP I antibodies in complexes with β2GP I as mediators of platelet activation, which can serve as a potential source contributing to thrombosis. We examined the involvement of the apolipoprotein E receptor 2' (apoER2') and glycoprotein I ba (GP I bα) in platelet activation induced by the anti-β2GP I /β2GP I complex. The interaction between the anti-β2GP I /β2GP I complex and platelets was examined using in vitro methods, in which the Fc portion of the antibody was immobilized using protein A coated onto a microtiter plate. Platelet activation was assessed by measuring GP II b/ III a activation and P-selectin expression and thromboxane B2 production as well as p38 mitogen-activated protein kinase phosphorylation. Our results revealed that the anti-β2GP I /β2GP I complex was able to activate platelets, and this activation was inhibited by either the anti-GP I bα antibody or the apoER2' inhibitor. Results showed that the anti-β2GP I /β2GP I complex induced platelet activation via GP I bα and apoER2', which may then contribute to the prothrombotic tendency in APS patients.
关键词: anti-β2GP I /β2GP I complex platelet GP I bα apoER2' thrombosis
Degradation of SARS-CoV-2 receptor ACE2 by the E3 ubiquitin ligase Skp2 in lung epithelial cells
Guizhen Wang, Qun Zhao, Hui Zhang, Fan Liang, Chen Zhang, Jun Wang, Zhenyin Chen, Ran Wu, Hong Yu, Beibei Sun, Hua Guo, Ruie Feng, Kaifeng Xu, Guangbiao Zhou
《医学前沿(英文)》 2021年 第15卷 第2期 页码 252-263 doi: 10.1007/s11684-021-0837-6
基于实时CT扫描技术的CO2和N2交替注入条件下煤吸附膨胀和解吸收缩规律研究 Article
Ranjith, Herbert E. Huppert
《工程(英文)》 2022年 第18卷 第11期 页码 88-95 doi: 10.1016/j.eng.2022.03.010
深部煤层是分布最广泛的适宜二氧化碳(CO2)地质封存的地层之一,且通常位于大型CO2排放源附近。将CO2注入到煤层中具有巨大的CO2封存潜力,同时可以提高煤层气的采收率(CO2-ECBM)。本文采用原位同步辐射X射线显微CT扫描技术,首次在原位条件下直接证明了注入氮气(N2)可以置换解吸CO2并减小因CO2吸附引起的煤基质膨胀研究结果表明,煤层中注入经过简单处理的烟道气(主要成分为N2和CO2),是技术上可行的CO2-ECBM 替代方案。其次,N2的存在可以使煤层保持较高的渗透率,实现长期CO2注入封存和煤层气增产。
Xiaofang Cui, Benting Ma, Yan Wang, Yan Chen, Chunling Shen, Ying Kuang, Jian Fei, Lungen Lu, Zhugang Wang
《医学前沿(英文)》 2019年 第13卷 第1期 页码 104-111 doi: 10.1007/s11684-017-0568-x
关键词: retinol dehydrogenase 13 carbon tetrachloride acute liver injury Cyp2e1 Spot14
用于CO甲烷化的Ni/CeO2催化剂还原过程重构行为调控研究 Article
曹昕宇, 浦天成, Bar Mosevitzky Lis, Israel E. Wachs, 彭冲, 朱明辉, 胡永康
《工程(英文)》 2022年 第14卷 第7期 页码 94-99 doi: 10.1016/j.eng.2021.08.023
还原预处理是活化负载型金属催化剂的重要步骤,但很少受到关注。本研究发现负载型镍催化剂的重构过程对预处理条件非常敏感。与使用氢气的传统活化方式相比,用合成气活化催化剂可以产生具有多晶结构的负载型镍纳米颗粒,其中包含丰富的晶界。独特的活化方式使得催化剂上CO吸附得到增强,提高了CO甲烷化率。通过操纵活化条件来调整催化剂结构的策略也可以被用于指导其他负载型金属催化剂的理性设计。
一种高效的异构车辆集群协同框架 Research Articles
Iftikhar AHMAD1,2,Rafidah Md NOOR2,Zaheed AHMED3,Umm-e-HABIBA3,Naveed AKRAM4, 5,Fausto Pedro GARCÍA MÁRQUEZ6
《信息与电子工程前沿(英文)》 2021年 第22卷 第9期 页码 1247-1259 doi: 10.1631/FITEE.2000260
Wei Wang,Bhavitavya Nijampatnam,Sadanandan E. Velu,Ruiwen Zhang
《化学科学与工程前沿(英文)》 2016年 第10卷 第1期 页码 1-15 doi: 10.1007/s11705-016-1562-6
关键词: synthesis marine drugs tricyclic pyrroloquinone alkaloid cancer therapy MDM2 p53
Competition for electrons between reductive dechlorination and denitrification
Lifeng Cao, Weihua Sun, Yuting Zhang, Shimin Feng, Jinyun Dong, Yongming Zhang, Bruce E. Rittmann
《环境科学与工程前沿(英文)》 2017年 第11卷 第6期 doi: 10.1007/s11783-017-0959-x
关键词: Competition for electrons Denitrification Reductive dechlorination Bioremediation Nitrate 2 4 6-trichlorophenol
吴剑,王世和
《中国工程科学》 2007年 第9卷 第11期 页码 191-195
为开发高效除磷脱氮技术,研制了将MBR与A2/O工艺有机集成的新型MB(A2/O)组合工艺。研究 了MB(A2/O)工艺处理城市污水的好氧、缺氧摄磷性能及微生物特性,并分析了其机理。结果表明:在 MB(A2/O)系统中,聚磷菌约占活性污泥总量的20%~40%,其中大量存在能够利用NOX-N作为电子受体 进行反硝化除磷的DPB,约占聚磷菌数量的35. 66%~67好氧摄磷的平均速率为2. 30mgP·gMLSS-1·h-1,最大摄磷速率为5. 44mgP·gMLSS-
标题 作者 时间 类型 操作
第三届环境、工业和能源工程国际会议(EI2E 2019)
2019年09月19日
会议信息
Effect of biochar amendment on soil’s retention capacity for estrogenic hormones from poultry manure treatment
Sukhjot MANN, Zhiming QI, Shiv O. PRASHER, Lanhai LI, Dongwei GUI, Qianjing JIANG
期刊论文
Anti-β glycoprotein I antibodies in complex with β2 glycoprotein I induce platelet activation via tworeceptors: apolipoprotein E receptor 2' and glycoprotein I bα
null
期刊论文
Degradation of SARS-CoV-2 receptor ACE2 by the E3 ubiquitin ligase Skp2 in lung epithelial cells
Guizhen Wang, Qun Zhao, Hui Zhang, Fan Liang, Chen Zhang, Jun Wang, Zhenyin Chen, Ran Wu, Hong Yu, Beibei Sun, Hua Guo, Ruie Feng, Kaifeng Xu, Guangbiao Zhou
期刊论文
Rdh13 deficiency weakens carbon tetrachloride-induced liver injury by regulating Spot14 and Cyp2e1 expression
Xiaofang Cui, Benting Ma, Yan Wang, Yan Chen, Chunling Shen, Ying Kuang, Jian Fei, Lungen Lu, Zhugang Wang
期刊论文
第四届设计、机械和材料工程国际会议(D2ME 2019)
2019年09月26日
会议信息
一种高效的异构车辆集群协同框架
Iftikhar AHMAD1,2,Rafidah Md NOOR2,Zaheed AHMED3,Umm-e-HABIBA3,Naveed AKRAM4, 5,Fausto Pedro GARCÍA MÁRQUEZ6
期刊论文
Discovery and development of synthetic tricyclic pyrroloquinone (TPQ) alkaloid analogs for human cancer therapy
Wei Wang,Bhavitavya Nijampatnam,Sadanandan E. Velu,Ruiwen Zhang
期刊论文
Competition for electrons between reductive dechlorination and denitrification
Lifeng Cao, Weihua Sun, Yuting Zhang, Shimin Feng, Jinyun Dong, Yongming Zhang, Bruce E. Rittmann
期刊论文
肖永红:临床高耐药与高毒性病原体共进化(2023年2月22日)
2023年03月10日
会议视频
第四届设计、机械和材料工程国际会议(D2ME 2019)
2019年09月26日
会议信息